Infographic: Salmonella Shuttle Tumor Antigens to Immune Cells

Following radiation therapy, which triggers the release of cancer-specific antigens, researchers injected Salmonella typhimurium bacteria covered in positively charged nano-particles near tumors in mice. The bacteria captured the negatively charged antigens and ferried them to dendritic cells in the tumors’ periphery, where a tumor-targeting immune response was initiated, improving the animals’ odds of survival.

Illustration showing how following radiation therapy, which triggers the release of cancer-specific antigens, researchers injected Salmonella typhimurium bacteria covered in positively charged nano- particles near tumors in mice.

© Kelly Finan

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Source: the-scientist.com

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