Cancer immunotherapies, such as infusions of CAR T cells, are effective for only a subset of patients. To develop more successful cell and gene therapies against cancer, researchers turn to single cell sequencing and immune profiling. These techniques help researchers understand the mechanisms behind varying patient responses, therapy resistance, and drug toxicity.
Download this research highlight from 10x Genomics to learn how scientists use single cell sequencing and immune profiling in cell and gene therapy research, including
- Enhancing T cell function by combining CRISPR screening with transcriptome analysis
- Assessing patient responses with immune profiling
- Tracking the evolution of infused T cells with single cell RNA sequencing (scRNA-seq)